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L.L. Brown

Publications and source records attributed to L.L. Brown.

3 recordsLinked to original sources

Enhancement of anti- Aeromonas salmonicida activity in Atlantic salmon ( Salmo salar ) macrophages by a mannose-binding lectin

We investigated the effects of a calcium-dependent mannose-binding lectin isolated from the serum of Atlantic salmon on Aeromonas salmonicida viability and the anti- A . salmonicida activity of Atlantic salmon macrophages. In the absence of other factors, binding of this lectin at concentrations of 0.8, 4.0 and 20.0 ng ml −1 to virulent A. salmonicida failed to significantly reduce ( P >0.05) cell viability. However, binding of the lectin to A. salmonicida did result in significant ( P ≤0.05) dose-dependent increases in phagocytosis, and bactericidal activity. Significant increases ( P ≤0.05) were also observed in phagocyte respiratory burst activity within the lectin concentration range of 4.0–20.0 ng ml −1 but the stimulation was not dose dependent at these lectin concentrations. At the lowest lectin concentration tested (0.32 ng ml −1 ), a significant decrease ( P ≤0.05) in respiratory burst was observed. The structure and activity of this lectin are similar to that of mammalian mannose-binding lectins, which are known to play a pivotal role in innate immunity. The presence of this lectin may be an important defense mechanism against Gram-negative bacteria such as A. salmonicida.

Comparative Biochemistry and Physiology, Part C: P↗

Volcanism and erosion during the past 930 k.y. at the Tatara-San Pedro complex, Chilean Andes

Geologic mapping, together with 73 new K-Ar and 40 Ar/ 39 Ar age determinations of 45 samples from 17 different volcanic units, plus paleomagnetic orientations, geochemical compositions, and terrestrial photogrammetry are used to define the chronostratigraphy of the Tatara–San Pedro complex, an eruptive center at 36°S on the volcanic front of the Andean southern volcanic zone. The Tatara–San Pedro complex preserves ≈55 km 3 of lavas that erupted from at least three central vent regions. Remnant, unconformity-bound sequences of lavas are separated by lacunae that include significant periods of erosion. Quaternary volcanism commenced ca. 930 ka with eruption of voluminous dacitic magma, followed 100 k.y. later by the only major rhyolitic eruption. From 780 ka onward, more than 80% of the preserved volume is basaltic andesite (52%–57% SiO 2 ), but petrographically and geochemically diverse dacitic magmas (63%–69% SiO 2 ) erupted sporadically throughout this younger, dominantly mafic phase of activity. A few basaltic lavas (49%–52% SiO 2 ) are present, mainly in portions of the complex older than 230 ka. The number of vents, the petrologic and geochemical diversity, and the temporal distribution of mafic and silicic lavas are consistent with emplacement of many separate batches of mafic magma into the shallow crust beneath the Tatara–San Pedro complex over the past million years.

Geological Society of America Bulletin↗

Recurrent eruption and subsidence at the Platoro caldera complex, southeastern San Juan volcanic field, Colorado: New tales from old tuffs

Reinterpretation of a voluminous regional ash-flow sheet (Masonic Park Tuff) as two separate tuff sheets of similar phenocryst-rich dacite erupted from separate source calderas has important implications for evolution of the multicyclic Platoro caldera complex and for caldera-forming processes generally. Masonic Park Tuff in central parts of the San Juan field, including the type area, was erupted from a concealed source at 28.6 Ma, but widespread tuff previously mapped as Masonic Park Tuff in the southeastern San Juan Mountains is the product of the youngest large-volume eruption of the Platoro caldera complex at 28.4 Ma. This large unit, newly named the “Chiquito Peak Tuff,” is the last-erupted tuff of the Treasure Mountain Group, which consists of at least 20 separate ash-flow sheets of dacite to low-silica rhyolite erupted from the Platoro complex during a 1 m.y. interval (29.5−28.4 Ma). Two Treasure Mountain tuff sheets have volumes in excess of 1000 km 3 each, and five more have volumes of 50–150 km 3 . The total volume of ash-flow tuff exceeds 2500 km 3 , and caldera-related lavas of dominantly andesitic composition make up 250-500 km 3 more. A much greater volume of intermediate-composition magma must have solidified in subcaldera magma chambers. Most preserved features of the Platoro complex-including postcollapse asymmetrical trap-door resurgent uplift of the ponded intracaldera tuff and concurrent infilling by andesitic lava flows-postdate eruption of the Chiquito Peak Tuff. The numerous large-volume pre-Chiquito Peak ash-flow tuffs document multiple eruptions accompanied by recurrent subsidence; early-formed caldera walls nearly coincide with margins of the later Chiquito Peak collapse. Repeated syneruptive collapse at the Platoro complex requires cumulative subsidence of at least 10 km. The rapid regeneration of silicic magmas requires the sustained presence of an andesitic subcaldera magma reservoir, or its rapid replenishment, during the 1 m.y. life span of the Platoro complex. Either case implies large-scale stoping and assimilative recycling of the Tertiary section, including intracaldera tuffs.

Colorado↗