Geology topics

John R. MacMillian

Publications and source records attributed to John R. MacMillian.

2 recordsLinked to original sources

USGS1989

Cytopathology and coagulopathy associated with viral erythrocytic necrosis in chum salmon

The 8-month cytopathologic progression of viral erythrocytic necrosis (VEN) disease in chum salmon Oncorhynchus keta is described. Single to multiple acidophilic, cytoplasmic viral inclusion bodies developed first in mature erythrocytes and then, within 1–2 months, all morphologically identifiable hemopoietic cell types contained VEN inclusions. Cytologic analysis indicated that multinucleate giant erythroblasts, ineffective erythropoiesis, and abnormal erythroid cell maturation occurred. A significant increase in blood coagulation time occurred concomitantly. This severe and chronic blood dyscrasia accounts for some of the pathophysiologic sequelae previously observed.

Journal of Aquatic Animal Health↗

USGS1979

Artificial transmission to and susceptibility of Puget Sound fish to viral erythrocytic necrosis (VEN)

In Puget Sound, Wash., the incidence of viral erythrocytic necrosis (VEN) varied geographically from 0 to 17% in chum salmon ( Oncorhynchus keta ) and from 4 to 59% in Pacific herring ( Clupea harengus pallasi ). The disease was experimentally transmitted by intraperitoneal injection to chum, pink ( O . gorbuscha ), coho ( O . kisutch ), chinook ( O . tshawytscha ), sockeye ( O . nerka ), and Atlantic ( Salmo salar ) salmon, and rainbow ( S . gairdneri ), brown ( S . trutta ), and brook ( Salvelinus fontinalis ) trout. The disease was transmitted to chum salmon and brook trout by waterborne virus. Virus obtained from herring was experimentally transmitted into chum salmon by intraperitoneal injection. Key words : viral erythrocytic necrosis, fish disease, transmission

Washington↗